The CXCL12γ Chemokine Displays Unprecedented Structural and Functional Properties that Make It a Paradigm of Chemoattractant Proteins

The CXCL12γ chemokine arises by alternative splicing from Cxcl12, an essential gene during development. This protein binds CXCR4 and displays an exceptional degree of conservation (99%) in mammals. CXCL12γ is formed by a protein core shared by all CXCL12 isoforms, extended by a highly cationic carbo...

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Detalles Bibliográficos
Autores principales: Rueda, Patricia, Balabanian, Karl, Lagane, Bernard, Staropoli, Isabelle, Chow, Ken, Levoye, Angelique, Laguri, Cedric, Sadir, Rabia, Delaunay, Thierry, Izquierdo, Elena, Pablos, Jose Luis, Lendinez, Elena, Caruz, Antonio, Franco, Diego, Baleux, Françoise, Lortat-Jacob, Hugues, Arenzana-Seisdedos, Fernando
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481281/
https://www.ncbi.nlm.nih.gov/pubmed/18648536
http://dx.doi.org/10.1371/journal.pone.0002543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481281/
https://www.ncbi.nlm.nih.gov/pubmed/18648536
http://dx.doi.org/10.1371/journal.pone.0002543

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