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The Complement Anaphylatoxin C5a Induces Apoptosis in Adrenomedullary Cells during Experimental Sepsis

Sepsis remains a poorly understood, enigmatic disease. One of the cascades crucially involved in its pathogenesis is the complement system. Especially the anaphylatoxin C5a has been shown to have numerous harmful effects during sepsis. We have investigated the impact of high levels of C5a on the adr...

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Detalles Bibliográficos
Autores principales: Flierl, Michael A., Rittirsch, Daniel, Chen, Anthony J., Nadeau, Brian A., Day, Danielle E., Sarma, J. Vidya, Huber-Lang, Markus S., Ward, Peter A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481299/
https://www.ncbi.nlm.nih.gov/pubmed/18648551
http://dx.doi.org/10.1371/journal.pone.0002560