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An Integrated Epigenetic and Genetic Analysis of DNA Methyltransferase Genes (DNMTs) in Tumor Resistant and Susceptible Chicken Lines

Both epigenetic alterations and genetic variations play essential roles in tumorigenesis. The epigenetic modification of DNA methylation is catalyzed and maintained by the DNA methyltransferases (DNMT3a, DNMT3b and DNMT1). DNA mutations and DNA methylation profiles of DNMTs themselves and their rela...

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Detalles Bibliográficos
Autores principales: Yu, Ying, Zhang, Huanmin, Tian, Fei, Zhang, Wensheng, Fang, Hongbin, Song, Jiuzhou
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481300/
https://www.ncbi.nlm.nih.gov/pubmed/18648519
http://dx.doi.org/10.1371/journal.pone.0002672