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An Integrated Epigenetic and Genetic Analysis of DNA Methyltransferase Genes (DNMTs) in Tumor Resistant and Susceptible Chicken Lines
Both epigenetic alterations and genetic variations play essential roles in tumorigenesis. The epigenetic modification of DNA methylation is catalyzed and maintained by the DNA methyltransferases (DNMT3a, DNMT3b and DNMT1). DNA mutations and DNA methylation profiles of DNMTs themselves and their rela...
Autores principales: | Yu, Ying, Zhang, Huanmin, Tian, Fei, Zhang, Wensheng, Fang, Hongbin, Song, Jiuzhou |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481300/ https://www.ncbi.nlm.nih.gov/pubmed/18648519 http://dx.doi.org/10.1371/journal.pone.0002672 |
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