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The CXC-Chemokine CXCL4 Interacts with Integrins Implicated in Angiogenesis

The human CXC-chemokine CXCL4 is a potent inhibitor of tumor-induced angiogenesis. Considering that CXCL4 is sequestered in platelet α-granules and released following platelet activation in the vicinity of vessel wall injury, we tested the hypothesis that CXCL4 might function as a ligand for integri...

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Detalles Bibliográficos
Autores principales: Aidoudi, Sallouha, Bujakowska, Kinga, Kieffer, Nelly, Bikfalvi, Andreas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481302/
https://www.ncbi.nlm.nih.gov/pubmed/18648521
http://dx.doi.org/10.1371/journal.pone.0002657