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Riluzole Increases the Amount of Latent HSF1 for an Amplified Heat Shock Response and Cytoprotection

BACKGROUND: Induction of the heat shock response (HSR) and increased expression of the heat shock proteins (HSPs) provide mechanisms to ensure proper protein folding, trafficking, and disposition. The importance of HSPs is underscored by the understanding that protein mis-folding and aggregation con...

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Detalles Bibliográficos
Autores principales: Yang, Jingxian, Bridges, Kristen, Chen, Kuang Yu, Liu, Alice Y.-C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481402/
https://www.ncbi.nlm.nih.gov/pubmed/18682744
http://dx.doi.org/10.1371/journal.pone.0002864