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Riluzole Increases the Amount of Latent HSF1 for an Amplified Heat Shock Response and Cytoprotection
BACKGROUND: Induction of the heat shock response (HSR) and increased expression of the heat shock proteins (HSPs) provide mechanisms to ensure proper protein folding, trafficking, and disposition. The importance of HSPs is underscored by the understanding that protein mis-folding and aggregation con...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481402/ https://www.ncbi.nlm.nih.gov/pubmed/18682744 http://dx.doi.org/10.1371/journal.pone.0002864 |