Inhibition of casein kinase 1-epsilon induces cancer-cell-selective, PERIOD2-dependent growth arrest

BACKGROUND: Kinases are under extensive investigation as targets for drug development. Discovering novel kinases whose inhibition induces cancer-cell-selective lethality would be of value. Recent advances in RNA interference have enabled the realization of this goal. RESULTS: We screened 5,760 short...

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Detalles Bibliográficos
Autores principales: Yang, Wan Seok, Stockwell, Brent R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481424/
https://www.ncbi.nlm.nih.gov/pubmed/18518968
http://dx.doi.org/10.1186/gb-2008-9-6-r92

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481424/
https://www.ncbi.nlm.nih.gov/pubmed/18518968
http://dx.doi.org/10.1186/gb-2008-9-6-r92

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