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Inhibition of casein kinase 1-epsilon induces cancer-cell-selective, PERIOD2-dependent growth arrest

BACKGROUND: Kinases are under extensive investigation as targets for drug development. Discovering novel kinases whose inhibition induces cancer-cell-selective lethality would be of value. Recent advances in RNA interference have enabled the realization of this goal. RESULTS: We screened 5,760 short...

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Detalles Bibliográficos
Autores principales:	Yang, Wan Seok, Stockwell, Brent R
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481424/ https://www.ncbi.nlm.nih.gov/pubmed/18518968 http://dx.doi.org/10.1186/gb-2008-9-6-r92

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