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Association of HMGB1 polymorphisms with outcome in patients with systemic inflammatory response syndrome

INTRODUCTION: High mobility group box 1 protein (HMGB1) is a pleiotropic cytokine, recently implicated in the pathophysiology of the systemic inflammatory response syndrome (SIRS) and sepsis. Data from experimental sepsis models show that administration of anti-HMGB1 antibodies significantly decreas...

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Detalles Bibliográficos
Autores principales: Kornblit, Brian, Munthe-Fog, Lea, Madsen, Hans O, Strøm, Jens, Vindeløv, Lars, Garred, Peter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481482/
https://www.ncbi.nlm.nih.gov/pubmed/18577209
http://dx.doi.org/10.1186/cc6935