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Association of HMGB1 polymorphisms with outcome in patients with systemic inflammatory response syndrome
INTRODUCTION: High mobility group box 1 protein (HMGB1) is a pleiotropic cytokine, recently implicated in the pathophysiology of the systemic inflammatory response syndrome (SIRS) and sepsis. Data from experimental sepsis models show that administration of anti-HMGB1 antibodies significantly decreas...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481482/ https://www.ncbi.nlm.nih.gov/pubmed/18577209 http://dx.doi.org/10.1186/cc6935 |