Antiproliferative and cytostatic effects of the natural product eupatorin on MDA-MB-468 human breast cancer cells due to CYP1-mediated metabolism

INTRODUCTION: The natural product eupatorin has been reported to have antiproliferative activity in tumour cell lines, but the exact mechanism is unclear. The cytochromes P450 CYP1B1, CYP1A1, and CYP1A2 have been shown to participate in the activation of various xenobiotics, compounds derived from t...

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Detalles Bibliográficos
Autores principales: Androutsopoulos, Vasilis, Arroo, Randolph RJ, Hall, John F, Surichan, Somchaiya, Potter, Gerry A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481486/
https://www.ncbi.nlm.nih.gov/pubmed/18454852
http://dx.doi.org/10.1186/bcr2090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481486/
https://www.ncbi.nlm.nih.gov/pubmed/18454852
http://dx.doi.org/10.1186/bcr2090

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