ATP-induced autophagy is associated with rapid killing of intracellular mycobacteria within human monocytes/macrophages

BACKGROUND: We have previously reported that ATP treatment of M bovis-BCG infected human macrophages induces P2X(7 )receptor-dependent killing of intracellular mycobacteria. The mechanism mediating this bactericidal effect has not been full characterized but is known to be Ca(2+)-dependent and to pr...

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Detalles Bibliográficos
Autores principales: Biswas, Debasis, Qureshi, Omar S, Lee, Wing-Yiu, Croudace, Joanne E, Mura, Manuela, Lammas, David A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483257/
https://www.ncbi.nlm.nih.gov/pubmed/18627610
http://dx.doi.org/10.1186/1471-2172-9-35

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483257/
https://www.ncbi.nlm.nih.gov/pubmed/18627610
http://dx.doi.org/10.1186/1471-2172-9-35

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