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Leukotriene B(4)-loaded microspheres: a new therapeutic strategy to modulate cell activation

BACKGROUND: Leukotriene B(4 )(LTB(4)) is a potent inflammatory mediator that also stimulates the immune response. In addition, it promotes polymorphonuclear leukocyte phagocytosis, chemotaxis, chemokinesis and modulates cytokines release. Regarding chemical instability of the leukotriene molecule, i...

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Detalles Bibliográficos
Autores principales: Nicolete, Roberto, Rius, Cristina, Piqueras, Laura, Jose, Peter J, Sorgi, Carlos A, Soares, Edson G, Sanz, Maria J, Faccioli, Lúcia H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483258/
https://www.ncbi.nlm.nih.gov/pubmed/18627613
http://dx.doi.org/10.1186/1471-2172-9-36