Estimation and testing for the effect of a genetic pathway on a disease outcome using logistic kernel machine regression via logistic mixed models

BACKGROUND: Growing interest on biological pathways has called for new statistical methods for modeling and testing a genetic pathway effect on a health outcome. The fact that genes within a pathway tend to interact with each other and relate to the outcome in a complicated way makes nonparametric m...

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Detalles Bibliográficos
Autores principales: Liu, Dawei, Ghosh, Debashis, Lin, Xihong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483287/
https://www.ncbi.nlm.nih.gov/pubmed/18577223
http://dx.doi.org/10.1186/1471-2105-9-292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483287/
https://www.ncbi.nlm.nih.gov/pubmed/18577223
http://dx.doi.org/10.1186/1471-2105-9-292

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