PRESTO: Rapid calculation of order statistic distributions and multiple-testing adjusted P-values via permutation for one and two-stage genetic association studies

BACKGROUND: Large-scale genetic association studies can test hundreds of thousands of genetic markers for association with a trait. Since the genetic markers may be correlated, a Bonferroni correction is typically too stringent a correction for multiple testing. Permutation testing is a standard sta...

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Detalles Bibliográficos
Autor principal: Browning, Brian L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483288/
https://www.ncbi.nlm.nih.gov/pubmed/18620604
http://dx.doi.org/10.1186/1471-2105-9-309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483288/
https://www.ncbi.nlm.nih.gov/pubmed/18620604
http://dx.doi.org/10.1186/1471-2105-9-309

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