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Analysis of heterogeneity and epistasis in physiological mixed populations by combined structural equation modelling and latent class analysis

BACKGROUND: Biological systems are interacting, molecular networks in which genetic variation contributes to phenotypic heterogeneity. This heterogeneity is traditionally modelled as a dichotomous trait (e.g. affected vs. non-affected). This is far too simplistic considering the complexity and genet...

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Detalles Bibliográficos
Autores principales: Fenger, Mogens, Linneberg, Allan, Werge, Thomas, Jørgensen, Torben
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483291/
https://www.ncbi.nlm.nih.gov/pubmed/18611252
http://dx.doi.org/10.1186/1471-2156-9-43