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Analysis of heterogeneity and epistasis in physiological mixed populations by combined structural equation modelling and latent class analysis
BACKGROUND: Biological systems are interacting, molecular networks in which genetic variation contributes to phenotypic heterogeneity. This heterogeneity is traditionally modelled as a dichotomous trait (e.g. affected vs. non-affected). This is far too simplistic considering the complexity and genet...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483291/ https://www.ncbi.nlm.nih.gov/pubmed/18611252 http://dx.doi.org/10.1186/1471-2156-9-43 |