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ACTH Inhibits bTREK-1 K(+) Channels through Multiple cAMP-dependent Signaling Pathways
Bovine adrenal zona fasciculata (AZF) cells express bTREK-1 K(+) channels that set the resting membrane potential and function pivotally in the physiology of cortisol secretion. Inhibition of these K(+) channels by adrenocorticotropic hormone (ACTH) or cAMP is coupled to depolarization and Ca(2+) en...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483331/ https://www.ncbi.nlm.nih.gov/pubmed/18663135 http://dx.doi.org/10.1085/jgp.200810003 |