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Ni(2+) Block of Ca(V)3.1 (α1G) T-type Calcium Channels
Ni(2+) inhibits current through calcium channels, in part by blocking the pore, but Ni(2+) may also allosterically affect channel activity via sites outside the permeation pathway. As a test for pore blockade, we examined whether the effect of Ni(2+) on Ca(V)3.1 is affected by permeant ions. We find...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483332/ https://www.ncbi.nlm.nih.gov/pubmed/18663132 http://dx.doi.org/10.1085/jgp.200809988 |