Cargando…

Wingless Signalling Alters the Levels, Subcellular Distribution and Dynamics of Armadillo and E-Cadherin in Third Instar Larval Wing Imaginal Discs

BACKGROUND: Armadillo, the Drosophila orthologue of vertebrate ß-catenin, plays a dual role as the key effector of Wingless/Wnt1 signalling, and as a bridge between E-Cadherin and the actin cytoskeleton. In the absence of ligand, Armadillo is phosphorylated and targeted to the proteasome. Upon bindi...

Descripción completa

Detalles Bibliográficos
Autores principales: Somorjai, Ildiko M. L., Martinez-Arias, Alfonso
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483348/
https://www.ncbi.nlm.nih.gov/pubmed/18682750
http://dx.doi.org/10.1371/journal.pone.0002893