Meiotic Recombination Hotspots of Fission Yeast Are Directed to Loci that Express Non-Coding RNA

BACKGROUND: Polyadenylated, mRNA-like transcripts with no coding potential are abundant in eukaryotes, but the functions of these long non-coding RNAs (ncRNAs) are enigmatic. In meiosis, Rec12 (Spo11) catalyzes the formation of dsDNA breaks (DSBs) that initiate homologous recombination. Most meiotic...

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Detalles Bibliográficos
Autores principales: Wahls, Wayne P., Siegel, Eric R., Davidson, Mari K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483352/
https://www.ncbi.nlm.nih.gov/pubmed/18682829
http://dx.doi.org/10.1371/journal.pone.0002887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483352/
https://www.ncbi.nlm.nih.gov/pubmed/18682829
http://dx.doi.org/10.1371/journal.pone.0002887

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