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Meiotic Recombination Hotspots of Fission Yeast Are Directed to Loci that Express Non-Coding RNA
BACKGROUND: Polyadenylated, mRNA-like transcripts with no coding potential are abundant in eukaryotes, but the functions of these long non-coding RNAs (ncRNAs) are enigmatic. In meiosis, Rec12 (Spo11) catalyzes the formation of dsDNA breaks (DSBs) that initiate homologous recombination. Most meiotic...
Autores principales: | Wahls, Wayne P., Siegel, Eric R., Davidson, Mari K. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483352/ https://www.ncbi.nlm.nih.gov/pubmed/18682829 http://dx.doi.org/10.1371/journal.pone.0002887 |
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