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Dorsomorphin, a Selective Small Molecule Inhibitor of BMP Signaling, Promotes Cardiomyogenesis in Embryonic Stem Cells

BACKGROUND: Pluripotent embryonic stem (ES) cells, which have the capacity to give rise to all tissue types in the body, show great promise as a versatile source of cells for regenerative therapy. However, the basic mechanisms of lineage specification of pluripotent stem cells are largely unknown, a...

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Detalles Bibliográficos
Autores principales: Hao, Jijun, Daleo, Marie A., Murphy, Clare K., Yu, Paul B., Ho, Joshua N., Hu, Jianyong, Peterson, Randall T., Hatzopoulos, Antonis K., Hong, Charles C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483414/
https://www.ncbi.nlm.nih.gov/pubmed/18682835
http://dx.doi.org/10.1371/journal.pone.0002904