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Induction of arthritis by high mobility group box chromosomal protein 1 is independent of tumour necrosis factor signalling

INTRODUCTION: TNFα and high mobility group box chromosomal protein 1 (HMGB1) are two potent proinflammatory cytokines implicated as important mediators of arthritis. Increased levels of these cytokines are found in the joints of rheumatoid arthritis patients, and the cytokines trigger arthritis when...

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Detalles Bibliográficos
Autores principales: Pullerits, Rille, Jonsson, Ing-Marie, Kollias, George, Tarkowski, Andrej
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483464/
https://www.ncbi.nlm.nih.gov/pubmed/18582368
http://dx.doi.org/10.1186/ar2445