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Induction of arthritis by high mobility group box chromosomal protein 1 is independent of tumour necrosis factor signalling
INTRODUCTION: TNFα and high mobility group box chromosomal protein 1 (HMGB1) are two potent proinflammatory cytokines implicated as important mediators of arthritis. Increased levels of these cytokines are found in the joints of rheumatoid arthritis patients, and the cytokines trigger arthritis when...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483464/ https://www.ncbi.nlm.nih.gov/pubmed/18582368 http://dx.doi.org/10.1186/ar2445 |