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A posteriori design of crystal contacts to improve the X-ray diffraction properties of a small RNA enzyme
The hairpin ribozyme is a small catalytic RNA comprising two helix–loop–helix domains linked by a four-way helical junction (4WJ). In its most basic form, each domain can be formed independently and reconstituted without a 4WJ to yield an active enzyme. The production of such minimal junctionless ha...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483500/ https://www.ncbi.nlm.nih.gov/pubmed/17582172 http://dx.doi.org/10.1107/S090744490702464X |