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Measurement of the formation of complexes in tyrosine kinase-mediated signal transduction

Isothermal titration calorimetry (ITC) provides highly complementary data to high-resolution structural detail. An overview of the methodology of the technique is provided. Ultimately, the correlation of the thermodynamic parameters determined by ITC with structural perturbation observed on going fr...

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Detalles Bibliográficos
Autor principal: Ladbury, John E.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483503/
https://www.ncbi.nlm.nih.gov/pubmed/17164523
http://dx.doi.org/10.1107/S0907444906046373