Activation of Gαi3 triggers cell migration via regulation of GIV

During migration, cells must couple direction sensing to signal transduction and actin remodeling. We previously identified GIV/Girdin as a Gαi3 binding partner. We demonstrate that in mammalian cells Gαi3 controls the functions of GIV during cell migration. We find that Gαi3 preferentially localize...

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Detalles Bibliográficos
Autores principales: Ghosh, Pradipta, Garcia-Marcos, Mikel, Bornheimer, Scott J., Farquhar, Marilyn G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483528/
https://www.ncbi.nlm.nih.gov/pubmed/18663145
http://dx.doi.org/10.1083/jcb.200712066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483528/
https://www.ncbi.nlm.nih.gov/pubmed/18663145
http://dx.doi.org/10.1083/jcb.200712066

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