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CHD5, a Tumor Suppressor Gene Deleted From 1p36.31 in Neuroblastomas

BACKGROUND: Neuroblastomas are characterized by hemizygous 1p deletions, suggesting that a tumor suppressor gene resides in this region. We previously mapped the smallest region of consistent deletion to a 2-Mb region of 1p36.31 that encodes 23 genes. Based on mutation analysis, expression pattern,...

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Detalles Bibliográficos
Autores principales: Fujita, Tomoyuki, Igarashi, Jun, Okawa, Erin R., Gotoh, Takahiro, Manne, Jayanthi, Kolla, Venkatadri, Kim, Jessica, Zhao, Huaqing, Pawel, Bruce R., London, Wendy B., Maris, John M., White, Peter S., Brodeur, Garrett M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483574/
https://www.ncbi.nlm.nih.gov/pubmed/18577749
http://dx.doi.org/10.1093/jnci/djn176