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High-Resolution Mapping of Gene Expression Using Association in an Outbred Mouse Stock
Quantitative trait locus (QTL) analysis is a powerful tool for mapping genes for complex traits in mice, but its utility is limited by poor resolution. A promising mapping approach is association analysis in outbred stocks or different inbred strains. As a proof of concept for the association approa...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483929/ https://www.ncbi.nlm.nih.gov/pubmed/18688273 http://dx.doi.org/10.1371/journal.pgen.1000149 |