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High-Resolution Mapping of Gene Expression Using Association in an Outbred Mouse Stock

Quantitative trait locus (QTL) analysis is a powerful tool for mapping genes for complex traits in mice, but its utility is limited by poor resolution. A promising mapping approach is association analysis in outbred stocks or different inbred strains. As a proof of concept for the association approa...

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Detalles Bibliográficos
Autores principales: Ghazalpour, Anatole, Doss, Sudheer, Kang, Hyun, Farber, Charles, Wen, Ping-Zi, Brozell, Alec, Castellanos, Ruth, Eskin, Eleazar, Smith, Desmond J., Drake, Thomas A., Lusis, Aldons J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483929/
https://www.ncbi.nlm.nih.gov/pubmed/18688273
http://dx.doi.org/10.1371/journal.pgen.1000149