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Non-Replication of Genome-Wide Based Associations between Common Variants in INSIG2 and PFKP and Obesity in Studies of 18,014 Danes

BACKGROUND: The INSIG2 rs7566605 and PFKP rs6602024 polymorphisms have been identified as obesity gene variants in genome-wide association (GWA) studies. However, replication has been contradictory for both variants. The aims of this study were to validate these obesity-associations through case-con...

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Detalles Bibliográficos
Autores principales: Andreasen, Camilla H., Mogensen, Mette S., Borch-Johnsen, Knut, Sandbæk, Annelli, Lauritzen, Torsten, Sørensen, Thorkild I. A., Hansen, Lars, Almind, Katrine, Jørgensen, Torben, Pedersen, Oluf, Hansen, Torben
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483934/
https://www.ncbi.nlm.nih.gov/pubmed/18682847
http://dx.doi.org/10.1371/journal.pone.0002872