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Induction of Olig2(+) Precursors by FGF Involves BMP Signalling Blockade at the Smad Level

During normal development oligodendrocyte precursors (OPCs) are generated in the ventral spinal cord in response to Sonic hedgehog (Shh) signalling. There is also a second, late wave of oligodendrogenesis in the dorsal spinal cord independent of Shh activity. Two signalling pathways, controlled by b...

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Detalles Bibliográficos
Autores principales: Bilican, Bilada, Fiore-Heriche, Christelle, Compston, Alastair, Allen, Nicholas D., Chandran, Siddharthan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483937/
https://www.ncbi.nlm.nih.gov/pubmed/18682850
http://dx.doi.org/10.1371/journal.pone.0002863