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Rudra Interrupts Receptor Signaling Complexes to Negatively Regulate the IMD Pathway

Insects rely primarily on innate immune responses to fight pathogens. In Drosophila, antimicrobial peptides are key contributors to host defense. Antimicrobial peptide gene expression is regulated by the IMD and Toll pathways. Bacterial peptidoglycans trigger these pathways, through recognition by p...

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Detalles Bibliográficos
Autores principales: Aggarwal, Kamna, Rus, Florentina, Vriesema-Magnuson, Christie, Ertürk-Hasdemir, Deniz, Paquette, Nicholas, Silverman, Neal
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483946/
https://www.ncbi.nlm.nih.gov/pubmed/18688280
http://dx.doi.org/10.1371/journal.ppat.1000120