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Rudra Interrupts Receptor Signaling Complexes to Negatively Regulate the IMD Pathway
Insects rely primarily on innate immune responses to fight pathogens. In Drosophila, antimicrobial peptides are key contributors to host defense. Antimicrobial peptide gene expression is regulated by the IMD and Toll pathways. Bacterial peptidoglycans trigger these pathways, through recognition by p...
Autores principales: | Aggarwal, Kamna, Rus, Florentina, Vriesema-Magnuson, Christie, Ertürk-Hasdemir, Deniz, Paquette, Nicholas, Silverman, Neal |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483946/ https://www.ncbi.nlm.nih.gov/pubmed/18688280 http://dx.doi.org/10.1371/journal.ppat.1000120 |
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