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Implication of TRIMalpha and TRIMCyp in interferon-induced anti-retroviral restriction activities

BACKGROUND: TRIM5α is a restriction factor that interferes with retroviral infections in a species-specific manner in primate cells. Although TRIM5α is constitutively expressed, its expression has been shown to be up-regulated by type I interferon (IFN). Among primates, a particular case exists in o...

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Detalles Bibliográficos
Autores principales: Carthagena, Laetitia, Parise, Mélanie C, Ringeard, Mathieu, Chelbi-Alix, Mounira K, Hazan, Uriel, Nisole, Sébastien
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483995/
https://www.ncbi.nlm.nih.gov/pubmed/18613956
http://dx.doi.org/10.1186/1742-4690-5-59