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Effector cell mediated cytotoxicity measured by intracellular Granzyme B release in HIV infected subjects

CD8+ cytotoxic T lymphocyte (CTL) activity is currently believed to be one of the key immunologic mechanisms responsible for the prevention or attenuation of HIV-1 infection. The induction of CD8+ T cell activation may also result in the production of soluble or non-classical lytic factors that are...

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Detalles Bibliográficos
Autores principales: Mahajan, Supriya D., Aalinkeel, Ravikumar, Schwartz, Stanley A., Chawda, Ram P., Nair, Madhavan P.N.
Formato: Texto
Lenguaje:English
Publicado: Biological Procedures Online 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC248472/
https://www.ncbi.nlm.nih.gov/pubmed/14615814
http://dx.doi.org/10.1251/bpo60