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The Effects of Alpha Interferon on the Development of Autoimmune Thyroiditis in the NOD H2h4 Mouse

Alpha interferon (αIFN) therapy is known to induce thyroid autoimmunity in up to 40% of patients. The mechanism is unknown, but Th1 switching has been hypothesized. The aim of our study was to examine whether αIFN accelerated the development of thyroiditis in genetically susceptible mice. We took ad...

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Detalles Bibliográficos
Autores principales: Oppenheim, Yael, Kim, Grace, Ban, Yoshiyuki, Unger, Pamela, Concepcion, Erlinda, Ando, Takao, Tomer, Yaron
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2485409/
https://www.ncbi.nlm.nih.gov/pubmed/14768947
http://dx.doi.org/10.1080/10446670310001642177