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Ablation of NK Cell Function During Tumor Growth Favors Type 2-Associated Macrophages, Leading to Suppressed CTL Generation

Several reports describe regulatory interactions between NK cells and CTLs. We addressed the issue of NK participation in the early anti-tumor defense by inoculating α-ASGM-1 treated mice with BW-Sp3 T lymphoma. Rejection of BW-Sp3 depends on strong CTL responses. Our results demonstrated that (i) N...

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Detalles Bibliográficos
Autores principales: Geldhof, Anja B., van Ginderachter, Jo A., Liu, Yuanqing, Noël, Wim, de Baetselier, Patrick
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2485417/
https://www.ncbi.nlm.nih.gov/pubmed/14768937
http://dx.doi.org/10.1080/10446670310001626580