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Efficient 1,4-addition of α-substituted fluoro(phenylsulfonyl)methane derivatives to α,β-unsaturated compounds

The 1,4-addition of a monofluoromethyl nucleophile to a variety of α,β-unsaturated compounds has been achieved under mild conditions using either phosphines or potassium carbonate at room temperature. α-Substituted fluoro(phenylsulfonyl)methane easily undergoes Michael addition to α,β-unsaturated ke...

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Detalles Bibliográficos
Autores principales: Prakash, G K Surya, Zhao, Xiaoming, Chacko, Sujith, Wang, Fang, Vaghoo, Habiba, Olah, George A
Formato: Texto
Lenguaje:English
Publicado: Beilstein-Institut 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2486456/
https://www.ncbi.nlm.nih.gov/pubmed/18941481
http://dx.doi.org/10.3762/bjoc.4.17