Construction of a cancer-perturbed protein-protein interaction network for discovery of apoptosis drug targets

BACKGROUND: Cancer is caused by genetic abnormalities, such as mutations of oncogenes or tumor suppressor genes, which alter downstream signal transduction pathways and protein-protein interactions. Comparisons of the interactions of proteins in cancerous and normal cells can shed light on the mecha...

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Detalles Bibliográficos
Autores principales: Chu, Liang-Hui, Chen, Bor-Sen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2488323/
https://www.ncbi.nlm.nih.gov/pubmed/18590547
http://dx.doi.org/10.1186/1752-0509-2-56

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2488323/
https://www.ncbi.nlm.nih.gov/pubmed/18590547
http://dx.doi.org/10.1186/1752-0509-2-56

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