Design considerations in a sib-pair study of linkage for susceptibility loci in cancer

BACKGROUND: Modern approaches to identifying new genes associated with disease allow very fine analysis of associaton and can be performed in population based case-control studies. However, the sibpair design is still valuable because it requires few assumptions other than acceptably high penetrance...

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Detalles Bibliográficos
Autores principales: Kerber, Richard A, Amos, Christopher I, Yeap, Beow Y, Finkelstein, Dianne M, Thomas, Duncan C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Technical Advance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2488325/
https://www.ncbi.nlm.nih.gov/pubmed/18616822
http://dx.doi.org/10.1186/1471-2350-9-64

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2488325/
https://www.ncbi.nlm.nih.gov/pubmed/18616822
http://dx.doi.org/10.1186/1471-2350-9-64

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