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Design considerations in a sib-pair study of linkage for susceptibility loci in cancer
BACKGROUND: Modern approaches to identifying new genes associated with disease allow very fine analysis of associaton and can be performed in population based case-control studies. However, the sibpair design is still valuable because it requires few assumptions other than acceptably high penetrance...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2488325/ https://www.ncbi.nlm.nih.gov/pubmed/18616822 http://dx.doi.org/10.1186/1471-2350-9-64 |