Evidence for the Mitochondrial Lactate Oxidation Complex in Rat Neurons: Demonstration of an Essential Component of Brain Lactate Shuttles

To evaluate the presence of components of a putative Intracellular Lactate Shuttle (ILS) in neurons, we attempted to determine if monocarboxylate (e.g. lactate) transporter isoforms (MCT1 and -2) and lactate dehydrogenase (LDH) are coexpressed in neuronal mitochondria of rat brains. Immunohistochemi...

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Detalles Bibliográficos
Autores principales: Hashimoto, Takeshi, Hussien, Rajaa, Cho, Hyung-Sook, Kaufer, Daniela, Brooks, George A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2488371/
https://www.ncbi.nlm.nih.gov/pubmed/18698340
http://dx.doi.org/10.1371/journal.pone.0002915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2488371/
https://www.ncbi.nlm.nih.gov/pubmed/18698340
http://dx.doi.org/10.1371/journal.pone.0002915

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