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Noise-Driven Stem Cell and Progenitor Population Dynamics

BACKGROUND: The balance between maintenance of the stem cell state and terminal differentiation is influenced by the cellular environment. The switching between these states has long been understood as a transition between attractor states of a molecular network. Herein, stochastic fluctuations are...

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Detalles Bibliográficos
Autores principales: Hoffmann, Martin, Chang, Hannah H., Huang, Sui, Ingber, Donald E., Loeffler, Markus, Galle, Joerg
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2488392/
https://www.ncbi.nlm.nih.gov/pubmed/18698344
http://dx.doi.org/10.1371/journal.pone.0002922