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Concurrence of Danish Dementia and Cataract: Insights from the Interactions of Dementia Associated Peptides with Eye Lens α-Crystallin

Familial Danish Dementia (FDD) is an autosomal disease, which is distinguished by gradual loss of vision, deafness, progressive ataxia and dementia. Cataract is the first manifestation of the disease. In this article, we demonstrate a specific correlation between the poisoning of the chaperone activ...

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Detalles Bibliográficos
Autores principales: Surolia, Ira, Sinha, Sharmistha, Sarkar, Debi Prasad, Reddy, P. Yadagiri, Reddy, G. Bhanuprakash, Surolia, Avadhesha
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2488398/
https://www.ncbi.nlm.nih.gov/pubmed/18698348
http://dx.doi.org/10.1371/journal.pone.0002927