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A Dynamic Stochastic Model for DNA Replication Initiation in Early Embryos

BACKGROUND: Eukaryotic cells seem unable to monitor replication completion during normal S phase, yet must ensure a reliable replication completion time. This is an acute problem in early Xenopus embryos since DNA replication origins are located and activated stochastically, leading to the random co...

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Detalles Bibliográficos
Autores principales: Goldar, Arach, Labit, Hélène, Marheineke, Kathrin, Hyrien, Olivier
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2488399/
https://www.ncbi.nlm.nih.gov/pubmed/18682801
http://dx.doi.org/10.1371/journal.pone.0002919