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Altered splicing of CEACAM1 in breast cancer: Identification of regulatory sequences that control splicing of CEACAM1 into long or short cytoplasmic domain isoforms

BACKGROUND: Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), a cell adhesion molecule expressed in a variety of cell types is a putative tumor suppressor gene. Alternative splicing of CEACAM1 generates 11 different splice variants, which include 1–4 ectodomains with either short...

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Detalles Bibliográficos
Autores principales: Gaur, Shikha, Shively, John E, Yen, Yun, Gaur, Rajesh K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2490704/
https://www.ncbi.nlm.nih.gov/pubmed/18507857
http://dx.doi.org/10.1186/1476-4598-7-46