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CD45 immunoaffinity depletion of vesicles from Jurkat T cells demonstrates that exosomes contain CD45: no evidence for a distinct exosome/HIV-1 budding pathway

The presence of relatively high levels of cellular protein contamination in density-purified virion preparations is a confounding factor in biochemical analyses of HIV and SIV produced from hematopoietic cells. A major source of this contamination is from vesicles, either microvesicles or exosomes,...

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Detalles Bibliográficos
Autores principales: Coren, Lori V, Shatzer, Teresa, Ott, David E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2490705/
https://www.ncbi.nlm.nih.gov/pubmed/18631400
http://dx.doi.org/10.1186/1742-4690-5-64