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Selective Constraints in Experimentally Defined Primate Regulatory Regions

Changes in gene regulation may be important in evolution. However, the evolutionary properties of regulatory mutations are currently poorly understood. This is partly the result of an incomplete annotation of functional regulatory DNA in many species. For example, transcription factor binding sites...

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Detalles Bibliográficos
Autores principales: Gaffney, Daniel J., Blekhman, Ran, Majewski, Jacek
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2490716/
https://www.ncbi.nlm.nih.gov/pubmed/18704158
http://dx.doi.org/10.1371/journal.pgen.1000157