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Dispatched Homolog 2 is targeted by miR-214 through a combination of three weak microRNA recognition sites

MicroRNAs (miRNAs) regulate gene expression by inhibiting translation of target mRNAs through pairing with miRNA recognition elements (MREs), usually in 3′ UTRs. Because pairing is imperfect, identification of bona fide mRNA targets presents a challenge. Most target recognition algorithms strongly e...

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Detalles Bibliográficos
Autores principales: Li, Nan, Flynt, Alex S., Kim, H. Rosemary, Solnica-Krezel, Lilianna, Patton, James G.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2490740/
https://www.ncbi.nlm.nih.gov/pubmed/18583362
http://dx.doi.org/10.1093/nar/gkn388