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The structure of the 5′-end of the protein-tyrosine phosphatase PTPRJ mRNA reveals a novel mechanism for translation attenuation

Analysis of the human protein-tyrosine phosphatase (PTP) PTPRJ mRNA detected three in-frame AUGs at the 5′-end (starting at nt +14, +191 and +356) with no intervening stop codons. This tandem AUG arrangement is conserved between humans and the mouse and is unique among the genes of the classical PTP...

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Detalles Bibliográficos
Autores principales: Karagyozov, Luchezar, Godfrey, Rinesh, Böhmer, Sylvia-Annette, Petermann, Astrid, Hölters, Sebastian, Östman, Arne, Böhmer, Frank-D.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2490741/
https://www.ncbi.nlm.nih.gov/pubmed/18603590
http://dx.doi.org/10.1093/nar/gkn391