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Systematic analysis of enzymatic DNA polymerization using oligo-DNA templates and triphosphate analogs involving 2′,4′-bridged nucleosides

In order to systematically analyze the effects of nucleoside modification of sugar moieties in DNA polymerase reactions, we synthesized 16 modified templates containing 2′,4′-bridged nucleotides and three types of 2′,4′-bridged nucleoside-5′-triphospates with different bridging structures. Among the...

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Detalles Bibliográficos
Autores principales: Kuwahara, Masayasu, Obika, Satoshi, Nagashima, Jun-ichi, Ohta, Yuki, Suto, Yoshiyuki, Ozaki, Hiroaki, Sawai, Hiroaki, Imanishi, Takeshi
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2490744/
https://www.ncbi.nlm.nih.gov/pubmed/18583360
http://dx.doi.org/10.1093/nar/gkn404